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 PostWysłany: Pią 20:25, 11 Mar 2011    Temat postu: tory burch reva utv ffa jwbk lyz Back to top

For idiopathic skin atrophy and atrophic lichen sclerosus in 1 case combined


larpsoriasisorapustulardragerul ~ on? BrJDermatol, 199g; 130t5l4.5spencer2M, SilversDN · GrossrmanME-Pustular 【l994-type project in 19 months to shake the same year locust Revised December 23) j Yi Yu Zhu commercial residential fiber look indistinct,[link widoczny dla zalogowanych], Xiao series group, operator 7 West to death for idiopathic skin atrophy and atrophic lichen sclerosus in 1 case combined} 8} 6. . . Sun Jian Fang Yuan 0 0 vehicles London high-fat Lie Mei 07f, f a general view that the current idiopathic skin atrophy established. But the P1A and LSA are rare skin disease, two patients (P1A), and lichen sclerosus et atrophicus (LSA) is two separate diseases, so far no report of two concomitant diseases, are met l down, the report is as follows. Male patient, l5 years old. 10 years ago, the left upper limb flexor side of the waist and place two gray-brown atrophic patches, slow growth, color change detectors, the number gradually increased, spread to the upper body. 7 years ago, were treated with partial closure of therapy (drug unknown) Department of lesions of the left shoulder treatment and 1 year occurred after local white papules, gradually increased, the integration into a sheet of white atrophic plaques, accompanied by mild itching. Physical examination; system check without exception. Dermatology: The back shows three gray-brown atrophic plaques, diameter 5 ~ l2cm, border clearance,[link widoczny dla zalogowanych], irregular shape, smooth surface, the bottom of vascular lesions clearly seek,[link widoczny dla zalogowanych], touch the soft. Flexor side of the left upper limb shows a similar skin lesions, but showed a broadband-like body longitudinally along the width of 2cm, length 20cm. Department of gray-brown atrophic plaques left shoulder with a 4cm × 5cm central large white atrophic plaques, irregular borders, surface shiny, touch hard (see photo 1). Gray-brown spots were taken and left shoulder and waist, white atrophic patches for the Department of Histopathology, lumbar lesion: epidermal atrophy, skin mutation level, superficial dermal blood vessels, appendages can be seen around the small amount of lymphocytic infiltration, thickening of dermal collagen fiber bundles in central , arranged in dense, mild hyaline degeneration, pathological diagnosis; meet the PIA to change. Shoulder lesions: hyperkeratosis with angle plug formation, basal cell liquefaction degeneration of dermal collagen fibers in the shallow Junichi of degeneration, which can be seen below the infiltration of inflammatory cells mainly lymphocytes (see photo 2), the pathological diagnosis LSA. Discussion: The patient comes first PIA, 3 years after Central appear LSA damage PIA lesions, two patients had typical clinical presentation and histopathology,[link widoczny dla zalogowanych], diagnosis can be merged into the accident is unlikely, if both of the there is some correlation between, it is noteworthy. (1) from the PIA and the LSA in terms of pathological changes, although the pathological changes of the two are not identical, but there are similarities, for example, two patients had dermal collagen fibers hyperplasia, sclerosis and hyaline degeneration of different degree, suggesting b disease may have similar pathological basis. (2) from the PIA and the relationship between LSA and scleroderma point of view, there are many reports P1A and LSA with scleroderma have a closer relationship, PIA can be transformed into scleroderma, or simultaneously with scleroderma exist '. LSA can also be combined with the existence of scleroderma], whether to prompt the PIA, scleroderma and LSA have a certain disease between the spectral correlation, and thus indirectly show the relationship between PIA and the LSA, it is worth consider risk. (3) from the cause of sense, although the PIA and the cause of LSA is not very clear,[link widoczny dla zalogowanych], but the similarities are all related with the trauma, lesions of the LSA patients after treatment occurred in the Bureau of letters, also supported the pathogenesis of trauma and LSA. In summary patients concomitant with the PIA and the LSA of view, it reveals the PIA and the LSA may be the same disease spectrum in the two diseases, it is worth further observation.


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