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Dołączył: 13 Gru 2010
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 Wysłany: Śro 15:45, 02 Mar 2011 Temat postu: Patients with acute myeloid leukemia serum cholest |
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Patients with acute myeloid leukemia and low-density lipoprotein cholesterol levels in the relationship between receptor activity
Cholesterol may also be caused by other mechanisms to induce leukemia cells IDI receptor, however,[link widoczny dla zalogowanych], IDI leukemia cells increased receptor activity can not be secondary to low blood cholesterol. First of all, after chemotherapy with peripheral blood leukemic cells disappeared,[link widoczny dla zalogowanych], serum cholesterol concentrations. Second,[link widoczny dla zalogowanych], about 80% of healthy people by the receptor clearance of plasma IDI, and the rest through the non-specific mechanisms. Clearance of LDL receptors on the IDI is extremely important,[link widoczny dla zalogowanych], therefore, the level of serum bile alcohol garden is also very important. Finally, the leukemia cells in serum-free culture medium and incubated lipoprotein period of time, can lead to IDI. Increased receptor activity and intracellular de novo cholesterol synthesis, however, added in the culture medium a small amount of IDI to prevent this phenomenon. IDI leukemia cells causes increased receptor activity is unclear, has confirmed that the lower cholesterol content of leukemia cells, which may lead to biofilm cells due to increased synthesis rates. It suggests biliary cells increased demand for nursery alcohol,[link widoczny dla zalogowanych], low cholesterol levels in leukemia cells led to I. DI receptor activity increased 0]. Our study confirmed that leukemia and other neoplastic diseases may be attributed to lower cholesterol IDI receptor activity of malignant cells increased to support this point of low malignant disease as a secondary phenomenon of hypercholesterolemia. Has been confirmed in vivo in many tumor cells IDI receptor activity increased, leukemia and other malignant cell receptor activity IDI IDI may become a target for the treatment of cancer based carrier ~. 4
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