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Pediatric primary disease complicated by drug-induced hematuria (20 cases analysis)
Benjamin was bright red, or l water samples. - Note 1 liter Lu held Aken 04ml liquid blood, the naked eye that Muse awareness. Taking business (18.0 ~ 2000 RPM / m min. For 5 minutes) 0.3ml solution for smears Shen, within view of each mirror the high to accompany more than 5 red blood cells to the naked eye can not detect microscopic hematuria who rhyme song. Hematuria caused many original solid, clear} system itself can be a disease or other infections, urinary tract stones. Urethral foreign body,[link widoczny dla zalogowanych], congenital malformations. Renal vascular disease and renal tumors. Systemic diseases can also be caused by difficulties. Drugs in the treatment of hematuria due to primary disease process. A direct result of the drugs themselves damage to the urinary organs, and to the integrity of damaged blood vessels and blood in the urine occurred. It is in the treatment of primary disease on the basis of the side effects of the drug caused the new disease. With no direct causal relationship between the primary disease, should be the original cast disease complications. 1.2 Overview the anti-inflammatory drugs, iodine amines, Qing Trappe cable, kanamycin and some other widely used drugs. Current gradually increased drug-induced renal damage. Pediatrics,[link widoczny dla zalogowanych], Tongji Hospital, Tongji Medical University, January 1989 ~ December 1992 fell 83 were treated in non-renal hematuria in 21 cases of drug-induced hematuria. 25.3. Also suggested that patients with renal dysfunction midship drug-related, drug-induced acute interstitial nephritis accounts for unexplained acute renal failure, renal biopsy lO ~ l4. 20 fall in this group of patients and bleeding in the past without kidney disease, were flooded after treatment hematuria and groan pay attention. Some of the abuse and non-objective combination, on the flu virus is obviously unreasonable application of gentamicin treatment. Some combination of two or more cases of kidney toxic drugs, no drugs, some indication, in some cases super-dose applications, the current super-dose of medication for the common celebration Trappe cable and anti-inflammatory drugs, some studies claim celebrate Trappe 6 ~ 8% after the application of any significant reduction in glomerular filtration rate in this group of patients taking the drug soon after hematuria. Obvious clinical signs and symptoms, after stopping to give the general treatment. Lu reported disappearance of the blood faster. Prognosis is good. The author believes that the primary disease in children during treatment. Must be strictly drug indications. As little as possible with or without renal toxicity of drugs. Prevent abuse, unlimited no purpose to increase the dose and combination therapy. Must be applied or combined drug treatment, monitoring of renal function when conditions permit. On the past history of kidney epilepsy, infant and newborn should pay attention. Prevent concurrent drug-induced hematuria. In the stem of a Gui Zhen Xi l Figure 3 Development of clinical pathogenesis mechanism of drug-induced hematuria is more complicated, the same drugs may be trapped in different mechanisms and produce different kidney damage. Currently divided into poisoning mechanism, the immune mechanism, inhibit the forefront of the synthesis of hydrazone 3 cable. Kidney damage caused by common drugs more than 2O. Prevalent in the amino-glycosides, semi-synthetic penicillin Faso, sulfa drugs,[link widoczny dla zalogowanych], antipyretic and analgesic. These drugs on the mechanism of renal damage and pathological changes need to be further explored. I clinical data of the 20 cases of male ld down. 6 females. Age l ~ l3 years old, under 3 years old 4. Cases, 4 to 7 years old 10 down, 8 ~ l3 years, 6 down. Primary disease was sepsis, 3 down, 6 cases of upper respiratory tract infection, pneumonia, 4 down, 3 cases of bacillary dysentery, encephalitis in 3 cases. Post-traumatic infection of the skin removed 1 2 patients taking sulfa drugs, metamizol 3 down. Ganmaotong 3 down. Aspirin in 2 cases. Intramuscular injection of compound aminopyrine 3 down, waste Trappe claim 5 cases analgin,[link widoczny dla zalogowanych], cold pass,[link widoczny dla zalogowanych], while the three sulfa drugs take 2 down, 2 of them large doses. Ignorant of the disease outside the original full uniform in all cases showed gross hematuria, or wash the meat in water samples. Mu-swollen eyes which the performance of 6 cases, 5 back pain knocked on kidney area. Oliguria 3 down. Urinary frequency, urgency, dysuria in 1. The patients did not find the bleeding point and purple rash malaria. No previous history of kidney disease. Urine in the urinary protein (+ + ~ H.) 3 cases, RBC (++~-}}}) 20 down. Routine blood test showed hemoglobin from <100g/L2 down, platelets and the clotting time were normal. Disabled immediately after the discovery of renal hematuria Village Ii drugs are harmful, water, bed rest, anti-infection with Penicillium rope, cord bleeding and apply life-drugs kidney problems symptomatic treatment by renal dysfunction. Consumer constricted time Bh1 gross hematuria down, 12h4 down. 24hl0 cases. 3Bh3 cases, 48h2 cases. Time of hematuria disappeared 2 days in 2 cases. 3 days in 8 cases, 5 days 7 down, 7 days in 2 cases, 8 days in 1 case. 0.5 to 1 year follow-up in 7 cases, 1 in 4, and 2 years in 2 cases, the phenomenon of good prognosis were not found in urine, ribs patients were cured. Eagle, a transcript of Xiang embroidery ~ hug chirp Lan
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