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 Wysłany: Śro 15:41, 23 Lut 2011 Temat postu: Apolipoprotein A1 gene polymorphisms and the effic |
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Apolipoprotein A1 gene polymorphisms and the efficacy of Qishenyiqi relevance of pills
o7 a l1-17) CorrelationbetweenApoA1genepolymorphismandefficacyofQishenYiqidrippingpillZHAOGuang · rong, ZHANGHeng-ming, XIAOMin,[link widoczny dla zalogowanych], etal (DepartmentofPharmaceuticalEngineering, CollegeofChemicalEngineeringandTechnologyofTi ~ mjinUniversity, Tianjin300072, China) Abstract: 【Objective】 Toexploretherelationshipbetweensinglenucleotidepolymorphism (SNP) ofapolipoproteinA1 (ApoA1) geneandefficacyofQishenYiqi (QSYQ) drippingpillsonqideficiencyandbloo,[link widoczny dla zalogowanych], tstasistypeofcoronaryheartdisease. [Methods】 Forty-twopatientsreceivedQSYQdrippingpillsforonemonth. Thesyndromeswerescored, andbloodsamplesweretakenbeforeandaftertreatment. Thecontentsofbloodfat, bloodsugarandapoAandapoBweredetectedandtheDNAwasextractedfromtheleukocyteofthebloodsamples, andthenthefirstextronofApoA1genewasamplifiedbypolymerasechainreaction. Thepolymorphicsitewasdetectedbysequencing. Re · suits】 【FoursignificantmutantsiteswerefoundinApoA1gene. Betweenmutantgroupsandnormalgroups, thesubtractvaluesofdeficiencyofvitalenergy, lassitude,[link widoczny dla zalogowanych], spontaneousperspiration, chestpain,[link widoczny dla zalogowanych], suffocativesensationinthechest,[link widoczny dla zalogowanych], palpitation, darkpurplefaceandtotalsyn-dromeSCOreweren'tsignificantlydifferent (P> 0.05). ThesubtractValuesofbloodglucose, triglyceride, andapolipoproteinsweren'talsosig-nificantlydifferent (P> 0.05). 【Conclusions】 FourSNPsitesinApoA1cann'taffecttheefficacyofQSYQdrippingpillsonqideficiencyandbloodstasistypeofcoronaryheartdisease. Keywords: ApolipoproteinA1 (ApoA1); singlenucleotidepolymorphism; QishenYiqidrippingpills; qideficiencyandbloodstasistypeofcoronaryheartdisease
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